DICHLOROACETATE AS A METABOLIC MODULATOR OF HEART MITOCHONDRIAL PROTEOME UNDER CONDITIONS OF REDUCED OXYGEN UTILIZATION

Dichloroacetate as a metabolic modulator of heart mitochondrial proteome under conditions of reduced oxygen utilization

Abstract Myocardial compensatory mechanisms stimulated by reduced oxygen utilization caused by streptozotocin-induced diabetes mellitus (DM) and treated with dichloroacetate (DCA) are presumably associated with the regulation of mitochondria.We aimed to promote the understanding of key signaling pathways and identify effectors involved in signal tr

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In Vivo Imaging of Xenograft Tumors Using an Epidermal Growth Factor Receptor-Specific Affibody Molecule Labeled with a Near-infrared Fluorophore

Overexpression of epidermal growth factor receptor (EGFR) is associated with many types of cancers.It is of great interest to noninvasively image Wall Accessory the EGFR expression in vivo.In this study, we labeled an EGFR-specific Affibody molecule (Eaff) with a near-infrared (NIR) dye IRDye800CW maleimide and tested the binding of this labeled mo

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Pattern of sucker development in cuttlefishes

Abstract Background Morphological novelties have been acquired Console and Display Board through evolutionary processes and related to the adaptation of new life-history strategies with new functions of the bodyparts.Cephalopod molluscs such as octopuses, squids and cuttlefishes possess unique morphological characteristics.Among those novel morphol

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