Dichloroacetate as a metabolic modulator of heart mitochondrial proteome under conditions of reduced oxygen utilization
Abstract Myocardial compensatory mechanisms stimulated by reduced oxygen utilization caused by streptozotocin-induced diabetes mellitus (DM) and treated with dichloroacetate (DCA) are presumably associated with the regulation of mitochondria.We aimed to promote the understanding of key signaling pathways and identify effectors involved in signal tr